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CS-W001157 4
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cis-Benzyl 3-hydroxycyclobutylcarbamate

  • CAS No. 1403766-86-8

  • Cat. No. CS-0049665
  • Purity≥98%
  • MDL No.MFCD23106304

*For research and further manufacturing use only, not for direct human use.

cis-Benzyl 3-hydroxycyclobutylcarbamate|CS-0049665

Structure of 1403766-86-8

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General Information

  • CAS No. 1403766-86-8
  • Cat. No. CS-0049665
  • Purity ≥98%
  • MDL No. MFCD23106304
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₅NO₃
  • Molecular Weight 221.26
  • Synonym(s) None
  • SMILES O[C@H]1C[C@H](C1)NC(=O)OCC1=CC=CC=C1

Description

cis-Benzyl 3-hydroxycyclobutylcarbamate features a rigid cyclobutane scaffold with stereochemically defined hydroxyl and carbamate groups, enabling precise spatial orientation in synthetic applications. This bench-stable intermediate integrates readily into complex molecular architectures, particularly in the development of constrained bioactive compounds and cyclic peptide analogs.

Application

cis-Benzyl 3-hydroxycyclobutylcarbamate serves as a versatile chiral building block for the synthesis of cyclobutane-containing heterocycles and bioactive scaffolds. The hydroxyl group enables selective derivatization, while the carbamate functionality offers stability and orthogonal protection. Its defined stereochemistry facilitates stereoselective transformations in medicinal chemistry campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   1.4361
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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