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CS-W001157 4
Total: USD 88.00

2-Amino-2-(4-fluorophenyl)ethan-1-ol

  • CAS No. 140373-17-7

  • Cat. No. CS-0088073
  • Purity≥97%
  • MDL No.MFCD11213644

*For research and further manufacturing use only, not for direct human use.

2-Amino-2-(4-fluorophenyl)ethan-1-ol|CS-0088073

Structure of 140373-17-7

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General Information

  • CAS No. 140373-17-7
  • Cat. No. CS-0088073
  • Purity ≥97%
  • MDL No. MFCD11213644
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀FNO
  • Molecular Weight 155.17
  • Synonym(s) Benzeneethanol, beta-amino-4-fluoro-
  • SMILES FC1=CC=C(C(N)CO)C=C1

Description

2-Amino-2-(4-fluorophenyl)ethan-1-ol features a chiral center flanked by an amino group and a hydroxyl function, enabling its use in asymmetric synthesis. The para-fluorophenyl moiety imparts enhanced electronic effects and metabolic stability. This bench-stable compound integrates readily into pharmaceutical intermediates and serves as a key scaffold for bioactive molecule construction.

Application

2-Amino-2-(4-fluorophenyl)ethan-1-ol serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of fluorinated amino alcohols and β-amino alcohol pharmacophores. Its bench-stable nature, combined with orthogonal functionality for further derivatization, facilitates efficient access to heterocyclic scaffolds and API intermediates via standard coupling, cyclization, or protection strategies.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.8178
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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