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CS-W001157 4
Total: USD 88.00

(S)-2-Amino-2-(4-fluorophenyl)ethan-1-ol

  • CAS No. 224434-01-9

  • Cat. No. CS-0088131
  • Purity≥97%
  • MDL No.MFCD09253714

*For research and further manufacturing use only, not for direct human use.

(S)-2-Amino-2-(4-fluorophenyl)ethan-1-ol|CS-0088131

Structure of 224434-01-9

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General Information

  • CAS No. 224434-01-9
  • Cat. No. CS-0088131
  • Purity ≥97%
  • MDL No. MFCD09253714
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀FNO
  • Molecular Weight 155.17
  • Synonym(s) Benzeneethanol, b-amino-4-fluoro-, (bS)-
  • SMILES FC1=CC=C([C@H](N)CO)C=C1

Description

(S)-2-Amino-2-(4-fluorophenyl)ethan-1-ol is a chiral building block featuring a primary amine and hydroxyl group flanking a stereogenic center. This configuration enables selective incorporation into bioactive molecules, particularly in the synthesis of pharmaceutical intermediates requiring defined stereochemistry. The fluorophenyl moiety enhances metabolic stability and modulates electronic properties, supporting efficient access to targeted compounds under standard conditions.

Application

(S)-2-Amino-2-(4-fluorophenyl)ethan-1-ol serves as a key chiral building block in the synthesis of bioactive molecules, particularly β-amino alcohols and pharmaceutical intermediates. Its well-defined stereochemistry enables stereoselective transformations, while the pendant amino and hydroxyl groups offer orthogonal reactivity for functionalization. The molecule exhibits good bench stability and facilitates efficient purification, making it suitable for iterative synthetic sequences in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.8178
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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