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Structure of 1402166-32-8
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This boronate-functional thiazole integrates seamlessly into Suzuki-Miyaura cross-coupling reactions under standard conditions. The tetramethyl-1,3,2-dioxaborolane moiety enhances stability and reactivity, while the bromine substituent enables orthogonal functionalization. Bench-stable and moisture-tolerant, this compound streamlines access to complex heteroaromatic architectures in medicinal chemistry and materials science.
2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole serves as a versatile Suzuki-Miyaura coupling building block, enabling efficient C–C bond formation under mild conditions. The boronate ester group exhibits excellent stability, facilitates straightforward purification, and tolerates a range of functional groups. Its thiazole core provides a rigid, electron-deficient heterocyclic scaffold commonly found in bioactive molecules, making it well-suited for medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: