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CS-W001157 4
Total: USD 88.00

Amlodipine impurity 6

  • CAS No. 140171-66-0

  • Cat. No. CS-0514003
  • Purity≥98%
  • MDL No.MFCD19704867

*For research and further manufacturing use only, not for direct human use.

Amlodipine impurity 6|CS-0514003

Structure of 140171-66-0

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General Information

  • CAS No. 140171-66-0
  • Cat. No. CS-0514003
  • Purity ≥98%
  • MDL No. MFCD19704867
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₂₃ClN₂O₅
  • Molecular Weight 394.85
  • Synonym(s) None
  • SMILES O=C(OC)C1=C(NC(=C(C(=O)OC)C1C=2C=CC=CC2Cl)COCCN)C

Synthesis

  • Route1
    • null|null
      140171-50-2
    • ~81%
    • Amlodipine impurity 6|CS-0514003
      140171-66-0

    References

    • ARTESIAN THERAPEUTICS, INC. Patent: WO2004/33444 A1, 2004 ; Location in patent: Page 30; 31-32 ; WO 2004/033444 A1
  • Route2
    • null|null
      156366-27-7
    • null|null
      98-11-3
    • ~%
    • Diethyl 2,6-bis((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate (Amlodipine Impurity)|CS-0531493
      331258-31-2
    • Amlodipine impurity 6|CS-0514003
      140171-66-0
    • In-stock
      Amlodipine besylate|CS-3988
      111470-99-6

    References

    • WO2003/101965 A1, ; Page 18; 19; 23-25 ;
  • Route3

    References

    • European Journal of Medicinal Chemistry, , vol. 26, # 9 p. 907 - 913

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06,GHS08,GHS09
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H318-H373-H410
Precautionary Statements : P260-P273-P280

Quality Control

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Computational Chemistry Data

  • TPSA   99.88
  • LogP   1.8762
  • H_Acceptors   7
  • H_Donors   2
  • Rotatable_Bonds   7

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