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CS-W001157 4
Total: USD 88.00

2,6-Dibromo-[1,2,4]triazolo[1,5-a]pyridine

  • CAS No. 1401624-81-4

  • Cat. No. CS-0101972
  • Purity≥98%
  • MDL No.MFCD26131653

*For research and further manufacturing use only, not for direct human use.

2,6-Dibromo-[1,2,4]triazolo[1,5-a]pyridine|CS-0101972

Structure of 1401624-81-4

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General Information

  • CAS No. 1401624-81-4
  • Cat. No. CS-0101972
  • Purity ≥98%
  • MDL No. MFCD26131653
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃Br₂N₃
  • Molecular Weight 276.92
  • Synonym(s) 2,6-dibromo-[1,2,4]-triazolo[1,5-a]pyridine
  • SMILES BrC1=CN2C(C=C1)=NC(Br)=N2

Description

2,6-Dibromo-[1,2,4]triazolo[1,5-a]pyridine features a rigid, electron-deficient heterocyclic core that integrates two bromine substituents at key positions, enabling direct functionalization in cross-coupling reactions. This bench-stable scaffold serves as a robust building block for advanced materials and pharmaceutical intermediates.

Application

2,6-Dibromo-[1,2,4]triazolo[1,5-a]pyridine serves as a versatile building block for the synthesis of functionalized triazolopyridine scaffolds. Its bromine substituents enable palladium-catalyzed cross-coupling reactions, facilitating the construction of biaryl and heteroaryl architectures with high regiocontrol. The molecule exhibits excellent bench stability and compatibility with diverse reaction conditions, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   30.19
  • LogP   2.2543
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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