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Structure of 14001-70-8
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2-(Methylthio)-5-nitropyrimidine features a pyrimidine core bearing a methylthio group at C2 and a nitro substituent at C5, delivering a potent electron-deficient heterocyclic scaffold. This configuration enables direct functionalization in cross-coupling reactions and facilitates incorporation into bioactive molecules. The compound exhibits robust stability under standard bench conditions and demonstrates favorable solubility in common organic solvents, streamlining handling in synthetic workflows.
2-(Methylthio)-5-nitropyrimidine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C2 position via cross-coupling reactions. Its methylthio group provides orthogonal reactivity for sulfur-directed transformations, while the nitro functionality facilitates sequential reduction and cyclization pathways. The compound exhibits excellent bench stability and compatibility with standard reaction conditions, simplifying purification and scale-up in synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: