Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Azido-PEG4-Amido-Tris

  • CAS No. 1398044-55-7

  • Cat. No. CS-0114921
  • Molecule weight394.42
  • Purity≥97%
  • MDL No.MFCD22574794

*For research and further manufacturing use only, not for direct human use.

Azido-PEG4-Amido-Tris|CS-0114921

Structure of 1398044-55-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1398044-55-7
  • Cat. No. CS-0114921
  • Purity ≥97%
  • MDL No. MFCD22574794
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₃₀N₄O₈
  • Molecular Weight 394.42
  • Synonym(s) None
  • SMILES O=C(NC(CO)(CO)CO)CCOCCOCCOCCOCCN=[N+]=[N-]

Description

N2-Et-dG, an adduct between DNA and the first metabolite of ethanol (acetaldehyde), strongly blocks transcription by RNA polymerases (RNAPs), including mammalian RNAPII and yeast RNAPII, E. coli RNAP, as well as T7 RNAP. All three of the multisubunit RNAPs incorporate a single rNTP residue opposite the N2-Et-dG lesion. The mammalian RNAPII exclusively incorporates cytidine monophosphate (CMP) opposite the N2-Et-dG lesion. The accessory transcription factor TFIIS does not usually act as a lesion bypass factor; instead, it stimulates the polymerase to remove the CMP incorporated opposite the lesion by mammalian RNAPII. N2-Et-dG reduces CTP incorporation by ~1500 fold.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   175.47
  • LogP   -1.4149
  • H_Acceptors   9
  • H_Donors   4
  • Rotatable_Bonds   19

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Azido-PEG4-Amido-Tris sigmaAzido-PEG4-Amido-Tris manufacturerAzido-PEG4-Amido-Tris priceAzido-PEG4-Amido-Tris structureAzido-PEG4-Amido-Tris SDSbuy Azido-PEG4-Amido-TrisAzido-PEG4-Amido-Tris supplierAzido-PEG4-Amido-Tris usesAzido-PEG4-Amido-Tris molecular weightprice of Azido-PEG4-Amido-TrisAzido-PEG4-Amido-Tris chemical name formula of Azido-PEG4-Amido-Tris
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label