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CS-W001157 4
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Pyridine-2,6-dicarboxamidine dihydrochloride

  • CAS No. 1394382-56-9

  • Cat. No. CS-0309755
  • Purity≥98%
  • MDL No.MFCD31718854

*For research and further manufacturing use only, not for direct human use.

Pyridine-2,6-dicarboxamidine dihydrochloride|CS-0309755

Structure of 1394382-56-9

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General Information

  • CAS No. 1394382-56-9
  • Cat. No. CS-0309755
  • Purity ≥98%
  • MDL No. MFCD31718854
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁Cl₂N₅
  • Molecular Weight 236.11
  • Synonym(s) None
  • SMILES NC(C1=NC(C(N)=N)=CC=C1)=N.Cl.Cl

Application

Pyridine-2,6-dicarboxamidine dihydrochloride serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient construction of nitrogen-rich heterocycles. Its amidine functionality offers strong hydrogen-bonding capacity and enhanced solubility, facilitating downstream derivatization in SPPS and macrocycle synthesis. The dihydrochloride salt form ensures excellent bench stability and ease of handling, while the pyridine core provides a rigid scaffold for structure-activity studies. Functions effectively in transition-metal-catalyzed couplings and amide bond formations under standard reaction conditions.

Safety Information

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Computational Chemistry Data

  • TPSA   112.63
  • LogP   0.49334
  • H_Acceptors   3
  • H_Donors   4
  • Rotatable_Bonds   2

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