Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

tert-Butyl (S)-(1,1,1-trifluoro-3-hydroxypropan-2-yl)carbamate

  • CAS No. 1393524-00-9

  • Cat. No. CS-0127814
  • Molecule weight229.20
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (S)-(1,1,1-trifluoro-3-hydroxypropan-2-yl)carbamate|CS-0127814

Structure of 1393524-00-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1393524-00-9
  • Cat. No. CS-0127814
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₄F₃NO₃
  • Molecular Weight 229.20
  • Synonym(s) TERT-BUTYL N-[(2S)-1,1,1-TRIFLUORO-3-HYDROXYPROPAN-2-YL]CARBAMATE
  • SMILES O=C(OC(C)(C)C)N[C@@H](CO)C(F)(F)F

Description

This chiral carbamate features a bench-stable trifluoromethyl group flanked by a hydroxy-bearing stereocenter, enabling selective protection of amines in complex synthesis. The tert-butyl moiety provides orthogonal deprotection under mild acidic conditions, while the (S)-configuration ensures high stereochemical fidelity in asymmetric transformations.

Application

tert-Butyl (S)-(1,1,1-trifluoro-3-hydroxypropan-2-yl)carbamate serves as a chiral building block for fluorinated synthons, enabling access to trifluoromethylated amino alcohols via mild deprotection. The protected hydroxyl group exhibits excellent bench stability and compatibility with diverse functional groups, facilitating its use in iterative synthesis of complex fluorinated scaffolds. Its orthogonal reactivity profile supports selective transformations in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   58.56
  • LogP   1.4343
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1393524-00-9 sigma1393524-00-9 manufacturer1393524-00-9 price1393524-00-9 structure1393524-00-9 SDSbuy 1393524-00-91393524-00-9 supplier1393524-00-9 uses1393524-00-9 molecular weightprice of 1393524-00-91393524-00-9 chemical name formula of 1393524-00-9
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label