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CS-W001157 4
Total: USD 88.00

1-Boc-3-Bromopiperidine

  • CAS No. 849928-26-3

  • Cat. No. CS-W005871
  • Purity≥95%
  • MDL No.MFCD07779077

*For research and further manufacturing use only, not for direct human use.

1-Boc-3-Bromopiperidine|CS-W005871

Structure of 849928-26-3

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General Information

  • CAS No. 849928-26-3
  • Cat. No. CS-W005871
  • Purity ≥95%
  • MDL No. MFCD07779077
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₈BrNO₂
  • Molecular Weight None
  • Synonym(s) Tert-butyl 3-bromopiperidine-1-carboxylate
  • SMILES N1(C(=O)OC(C)(C)C)CC(Br)CCC1

Description

1-Boc-3-Bromopiperidine features a bromine-substituted piperidine ring protected at nitrogen with a tert-butoxycarbonyl group. This stable, bench-ready derivative enables direct incorporation into cross-coupling reactions and facilitates the synthesis of complex nitrogen-containing scaffolds under mild conditions.

Application

1-Boc-3-bromopiperidine serves as a versatile building block in medicinal chemistry, enabling efficient access to brominated piperidine scaffolds. The Boc group provides stability and orthogonal deprotection, while the pendant bromide facilitates palladium-catalyzed cross-coupling reactions. Its bench-stable solid form and compatibility with standard synthetic workflows make it well-suited for iterative diversification in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335-H410
Precautionary Statements : P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362+P364-P391-P405-P501

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   2.7808
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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