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Bromo-PEG4-acid

  • CAS No. 1393330-38-5

  • Cat. No. CS-0114614
  • Purity≥97%
  • MDL No.MFCD22574799

*For research and further manufacturing use only, not for direct human use.

Bromo-PEG4-acid|CS-0114614

Structure of 1393330-38-5

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General Information

  • CAS No. 1393330-38-5
  • Cat. No. CS-0114614
  • Purity ≥97%
  • MDL No. MFCD22574799
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₁BrO₆
  • Molecular Weight 329.18
  • Synonym(s) None
  • SMILES O=C(O)CCOCCOCCOCCOCCBr

Description

Bromo-PEG4-acid features a reactive bromide terminus paired with a four-ethylene glycol spacer and a carboxylic acid group. This trifunctional architecture enables site-specific conjugation in bioconjugation workflows, offering enhanced solubility and stability under standard conditions. The pendant acid facilitates coupling via amine activation, while the PEG4 chain reduces non-specific binding.

Application

Bromo-PEG4-acid serves as a versatile bifunctional linker for conjugation and polymer synthesis. The bromo group enables efficient nucleophilic substitution with amines or thiols, while the terminal carboxylic acid facilitates amide coupling or activation via common reagents. Its PEG4 spacer provides enhanced solubility and reduced aggregation, making it ideal for bioconjugation, drug delivery systems, and surface functionalization applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   74.22
  • LogP   0.9224
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   14

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