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CS-W001157 4
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5,6-Dihydroxyindoline hydrobromide

  • CAS No. 138937-28-7

  • Cat. No. CS-0209156
  • Molecule weight232.07
  • Purity≥97%
  • MDL No.MFCD07368401

*For research and further manufacturing use only, not for direct human use.

5,6-Dihydroxyindoline hydrobromide|CS-0209156

Structure of 138937-28-7

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General Information

  • CAS No. 138937-28-7
  • Cat. No. CS-0209156
  • Purity ≥97%
  • MDL No. MFCD07368401
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀BrNO₂
  • Molecular Weight 232.07
  • Synonym(s) Indoline-5,6-diol hydrobromide
  • SMILES C1CNC2=CC(=C(C=C12)O)O.Br

Description

5,6-Dihydroxyindoline hydrobromide features a fused bicyclic core with two adjacent hydroxyl groups, enhancing solubility and reactivity. This bench-stable derivative integrates readily into synthetic sequences requiring oxygen-rich heterocyclic scaffolds. The hydrobromide salt form improves handling and crystallization behavior in process development workflows.

Application

5,6-Dihydroxyindoline hydrobromide serves as a stable, bench-ready building block for the synthesis of substituted indolines and oxindoles. Its dual hydroxyl groups enable facile derivatization via oxidation, etherification, or metal-catalyzed coupling reactions. The hydrobromide salt enhances solubility and handling, facilitating use in aqueous or polar organic media. Functions effectively in the construction of bioactive heterocycles relevant to medicinal chemistry and natural product synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H410
Precautionary Statements : P273-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.49
  • LogP   1.6437
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   0

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