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CS-W001157 4
Total: USD 88.00

2-(Diphenylphosphino)biphenyl

  • CAS No. 13885-09-1

  • Cat. No. CS-W003792
  • Purity≥97%
  • MDL No.MFCD11559063

*For research and further manufacturing use only, not for direct human use.

2-(Diphenylphosphino)biphenyl|CS-W003792

Structure of 13885-09-1

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General Information

  • CAS No. 13885-09-1
  • Cat. No. CS-W003792
  • Purity ≥97%
  • MDL No. MFCD11559063
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₁₉P
  • Molecular Weight 338.38
  • Synonym(s) biphenyl-2-yl(diphenyl)phosphane; 2-(Diphenylphosphino)biphenyl
  • SMILES P(C1=CC=CC=C1)(C2=CC=CC=C2C3=CC=CC=C3)C4=CC=CC=C4

Description

Fmoc-N-amido-PEG10-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Synthesis

  • Route1
    • In-stock
      2-Iodo-1,1'-biphenyl|CS-W007659
      2113-51-1
    • null|null
      829-85-6
    • ~81%
    • In-stock
      2-(Diphenylphosphino)biphenyl|CS-W003792
      13885-09-1

    References

    • Gelman, Dmitri; Jiang, Lei; Buchwald, Stephen L. Organic Letters, 2003 , vol. 5, # 13 p. 2315 - 2318
  • Route2
    • null|null
      1942-82-1
    • ~77%
    • In-stock
      2-(Diphenylphosphino)biphenyl|CS-W003792
      13885-09-1

    References

    • Baillie, Colin; Xiao, Jianliang Tetrahedron, 2004 , vol. 60, # 19 p. 4159 - 4168
  • Route3
    • In-stock
      2-Bromobiphenyl|CS-W001914
      2052-07-5
    • null|null
      1079-66-9
    • ~65%
    • In-stock
      2-(Diphenylphosphino)biphenyl|CS-W003792
      13885-09-1

    References

    • Wang, Weibo; Hammond, Gerald B.; Xu, Bo Journal of the American Chemical Society, 2012 , vol. 134, # 12 p. 5697 - 5705

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   5.1118
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   4

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