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(S)-Methyl 2-amino-2-cyclopropylacetate hydrochloride

  • CAS No. 138326-68-8

  • Cat. No. CS-0150941
  • Molecule weight165.62
  • Purity≥97%
  • MDL No.MFCD09607984

*For research and further manufacturing use only, not for direct human use.

(S)-Methyl 2-amino-2-cyclopropylacetate hydrochloride|CS-0150941

Structure of 138326-68-8

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General Information

  • CAS No. 138326-68-8
  • Cat. No. CS-0150941
  • Purity ≥97%
  • MDL No. MFCD09607984
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO₂
  • Molecular Weight 165.62
  • Synonym(s) S-Cyclopropylglycine Methyl ester hydrochloride
  • SMILES COC(=O)[C@H](C1CC1)N.Cl

Description

(S)-Methyl 2-amino-2-cyclopropylacetate hydrochloride features a chiral cyclopropyl scaffold that imparts distinct stereochemical control in asymmetric synthesis. The amine functionality enables direct derivatization, while the hydrochloride salt enhances solubility and stability under standard handling conditions. This compound serves as a key building block for bioactive molecules requiring defined stereocenters.

Application

(S)-Methyl 2-amino-2-cyclopropylacetate hydrochloride serves as a stereochemically defined building block for the synthesis of bioactive molecules, particularly in medicinal chemistry. Its cyclopropyl moiety imparts conformational rigidity, while the protected amine and ester functionalities enable orthogonal transformations. The compound exhibits excellent bench stability and facilitates efficient coupling reactions, making it well-suited for modular peptide and heterocycle construction.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.3185
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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