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Bromo-PEG2-C2-Boc

  • CAS No. 1381861-91-1

  • Cat. No. CS-0114591
  • Purity≥96%
  • MDL No.MFCD22574821

*For research and further manufacturing use only, not for direct human use.

Bromo-PEG2-C2-Boc|CS-0114591

Structure of 1381861-91-1

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General Information

  • CAS No. 1381861-91-1
  • Cat. No. CS-0114591
  • Purity ≥96%
  • MDL No. MFCD22574821
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₁BrO₄
  • Molecular Weight 297.19
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCOCCBr

Description

Bromo-PEG2-C2-Boc features a bromide electrophile flanked by a short PEG2 spacer and a C2 linker, terminating in a Boc-protected amine. This bifunctional reagent enables site-specific conjugation under mild conditions, with the Boc group providing stability during synthesis and allowing for controlled deprotection. Designed for precise bioconjugation workflows.

Application

Bromo-PEG2-C2-Boc serves as a versatile bifunctional building block for conjugation and polymer synthesis. The bromo group enables efficient nucleophilic substitution, while the PEG2 spacer provides solubility and biocompatibility. The C2-Boc moiety offers a stable, orthogonal protecting group readily removed under mild acidic conditions. This combination facilitates precise functionalization in peptide-drug conjugates, dendrimer assembly, and surface modification applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   44.76
  • LogP   2.1463
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   8

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