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CS-W001157 4
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(4-Aminopyridin-3-yl)methanol

  • CAS No. 138116-34-4

  • Cat. No. CS-0044077
  • Purity≥95%
  • MDL No.MFCD06203066

*For research and further manufacturing use only, not for direct human use.

(4-Aminopyridin-3-yl)methanol|CS-0044077

Structure of 138116-34-4

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General Information

  • CAS No. 138116-34-4
  • Cat. No. CS-0044077
  • Purity ≥95%
  • MDL No. MFCD06203066
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O
  • Molecular Weight 124.14
  • Synonym(s) 4-AMINOPYRIDINE-3-METHANOL
  • SMILES OCC1=C(N)C=CN=C1

Description

m-PEG24-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.

Synthesis

  • Route1

    References

    • Thomas, Allen A.; Le Huerou; De Meese; Gunawardana, Indrani; Kaplan, Tomas; Romoff, Todd T.; Gonzales, Stephen S.; Condroski, Kevin; Boyd, Steven A.; Ballard, Josh; Bernat, Bryan; DeWolf, Walter; Han, May; Lee, Patrice; Lemieux, Christine; Pedersen, Robin; Pheneger, Jed; Poch, Greg; Smith, Darin; Sullivan, Francis; Weiler, Solly; Wright, S. Kirk; Lin, Jie; Brandhuber, Barb; Vigers, Guy Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 6 p. 2206 - 2210
  • Route2

    References

    • Leroy; Despres; Bigan; Blondeau Synthetic Communications, 1996 , vol. 26, # 12 p. 2257 - 2272
  • Route3
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      1003-73-2
    • ~%
    • (4-Aminopyridin-3-yl)methanol|CS-0044077
      138116-34-4

    References

    • Synthetic Communications, , vol. 26, # 12 p. 2257 - 2272

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS09
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅱ
Hazard Statements : H300-H315-H319-H335-H411
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.14
  • LogP   0.1561
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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