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CS-W001157 4
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tert-Butyl N-methyl-N-(piperidin-4-ylmethyl)carbamate

  • CAS No. 138022-04-5

  • Cat. No. CS-W019860
  • Purity≥95%
  • MDL No.MFCD06800387

*For research and further manufacturing use only, not for direct human use.

tert-Butyl N-methyl-N-(piperidin-4-ylmethyl)carbamate|CS-W019860

Structure of 138022-04-5

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General Information

  • CAS No. 138022-04-5
  • Cat. No. CS-W019860
  • Purity ≥95%
  • MDL No. MFCD06800387
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₄N₂O₂
  • Molecular Weight 228.34
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N(C)CC1CCNCC1

Description

tert-Butyl N-methyl-N-(piperidin-4-ylmethyl)carbamate features a protected amine scaffold with a piperidinylmethyl side chain, enabling seamless integration into complex molecular architectures. This bench-stable carbamate delivers selective nitrogen functionalization under mild deprotection conditions, streamlining synthesis in medicinal chemistry and peptide derivatization workflows.

Application

tert-Butyl N-methyl-N-(piperidin-4-ylmethyl)carbamate serves as a versatile, bench-stable building block for medicinal chemistry and process synthesis. Its orthogonal protection profile enables selective deprotection of the carbamate while preserving the tertiary amine and piperidine functionality. It facilitates efficient access to complex nitrogen-containing scaffolds via standard coupling, reductive amination, and cyclization protocols, with excellent functional group tolerance and straightforward purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.8529
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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