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Structure of 1379457-78-9
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6-Bromo-3-fluoropyridin-2-amine features a strategically positioned bromo and fluoro substitution on the pyridine core, enabling selective cross-coupling reactions. The amine group provides a reactive handle for diversification, while the electron-deficient ring enhances compatibility with palladium-catalyzed transformations. This scaffold exhibits excellent stability under standard reaction conditions.
6-Bromo-3-fluoropyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the ortho-fluoro substituent enhances electrophilicity for nucleophilic aromatic substitution. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: