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CS-W001157 4
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(4S,​4'S)​-2,​2'-​Cyclopentylidenebis[​4,​5-​dihydro-​4-isopropyloxazole]

  • CAS No. 1379452-52-4

  • Cat. No. CS-0086890
  • Purity≥95%
  • MDL No.MFCD24849484

*For research and further manufacturing use only, not for direct human use.

(4S,​4'S)​-2,​2'-​Cyclopentylidenebis[​4,​5-​dihydro-​4-isopropyloxazole]|CS-0086890

Structure of 1379452-52-4

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General Information

  • CAS No. 1379452-52-4
  • Cat. No. CS-0086890
  • Purity ≥95%
  • MDL No. MFCD24849484
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₈N₂O₂
  • Molecular Weight 292.42
  • Synonym(s) 2,2'-(cyclopentane-1,1-diyl)bis(4-isopropyl-4,5-dihydrooxazole)
  • SMILES CC(C)[C@H]1COC(C2(C3=N[C@@H](C(C)C)CO3)CCCC2)=N1

Description

This chiral bis-oxazole scaffold features a rigid cyclopentylidene bridge enabling precise spatial control in asymmetric synthesis. The 4,5-dihydro-4-isopropyloxazole rings offer enhanced stability and solubility, while the (4S,4'S) stereochemistry ensures high enantioselectivity in catalytic applications.

Application

(4S,4'S)-2,2'-Cyclopentylidenebis[4,5-dihydro-4-isopropyloxazole] serves as a chiral bis-oxazoline ligand that enables efficient asymmetric catalysis in transition-metal-mediated reactions. Its rigid cyclopentylidene backbone imparts high stereocontrol, while the isopropyl-substituted oxazole rings offer enhanced bench stability and ease of purification. The structure facilitates enantioselective C–C bond formation and functions reliably in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   3.4534
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

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