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Structure of 1379334-91-4
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8-Chloroquinolin-7-amine is a heterocyclic amine featuring a chlorine atom at the 8-position and a primary amine at the 7-position of the quinoline scaffold. This electron-deficient architecture enables direct incorporation into metal-ligand complexes and facilitates C–N coupling reactions under mild conditions. The molecule exhibits enhanced solubility in polar organic solvents and stability under ambient handling, making it a practical building block for pharmaceutical intermediates and functional materials.
8-Chloroquinolin-7-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of quinoline-based scaffolds. Its chlorine and amine functionalities provide orthogonal reactivity for Suzuki-Miyaura couplings, nucleophilic substitutions, and metal-catalyzed C–H functionalizations. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in API development and target-oriented discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: