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CS-W001157 4
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(1-(Dimethylamino)cyclobutyl)methanol

  • CAS No. 1378667-67-4

  • Cat. No. CS-0434134
  • Molecule weight129.20
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1-(Dimethylamino)cyclobutyl)methanol|CS-0434134

Structure of 1378667-67-4

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General Information

  • CAS No. 1378667-67-4
  • Cat. No. CS-0434134
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₅NO
  • Molecular Weight 129.20
  • Synonym(s) [1-(Dimethylamino)cyclobutyl]methanol
  • SMILES OCC1(N(C)C)CCC1

Description

This cyclobutylmethanol derivative features a dimethylamino group that enhances solubility and nucleophilicity, enabling efficient incorporation into bioconjugation workflows. The scaffold offers robust stability under standard conditions and serves as a versatile building block in medicinal chemistry.

Application

(1-(Dimethylamino)cyclobutyl)methanol serves as a versatile building block in medicinal chemistry, enabling the construction of saturated heterocyclic scaffolds through standard functionalization. Its cyclobutyl core offers conformational rigidity, while the pendant dimethylamino group provides moderate basicity and enhanced solubility. The primary alcohol facilitates straightforward derivatization via esterification, ether formation, or oxidation, supporting efficient route optimization. Bench-stable and compatible with common reaction conditions, it functions effectively in multi-step syntheses requiring controlled stereochemistry and functional group tolerance.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H302-H315-H318-H335
Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501

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Computational Chemistry Data

  • TPSA   23.47
  • LogP   0.463
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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