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CS-W001157 4
Total: USD 88.00

3-(4-Fluorobenzyl)-1,3-thiazolidine-2,4-dione

  • CAS No. 137660-67-4

  • Cat. No. CS-0116986
  • Molecule weight225.24
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(4-Fluorobenzyl)-1,3-thiazolidine-2,4-dione|CS-0116986

Structure of 137660-67-4

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General Information

  • CAS No. 137660-67-4
  • Cat. No. CS-0116986
  • Purity ≥97%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈FNO₂S
  • Molecular Weight 225.24
  • Synonym(s) 2,4-Thiazolidinedione, 3-[(4-fluorophenyl)methyl]-
  • SMILES O=C(N1CC2=CC=C(F)C=C2)SCC1=O

Synthesis

  • Route1

    References

    • Albers, Harald M. H. G.; Van Meeteren, Laurens A.; Egan, David A.; Van Tilburg, Erica W.; Moolenaar, Wouter H.; Ovaa, Huib Journal of Medicinal Chemistry, 2010 , vol. 53, # 13 p. 4958 - 4967
  • Route2
    • 2,4-Thiazolidinedione, potassium salt 1:1|CS-0348311
      39131-10-7
    • ~94%
    • 3-(4-Fluorobenzyl)-1,3-thiazolidine-2,4-dione|CS-0116986
      137660-67-4

    References

    • Nitsche, Christoph; Schreier, Verena N.; Behnam, Mira A. M.; Kumar, Anil; Bartenschlager, Ralf; Klein, Christian D. Journal of Medicinal Chemistry, 2013 , vol. 56, # 21 p. 8389 - 8403
  • Route3

    References

    • Bozdag-Duendar, Oya; Ceylan-Uenluesoy, Meltem; Verspohl, Eugen J.; Ertan, Rahmiye Arzneimittel-Forschung/Drug Research, 2007 , vol. 57, # 8 p. 532 - 536

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   37.38
  • LogP   2.0211
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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