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Structure of 137654-20-7
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2-Fluoro-3-methoxybenzoic acid features a strategically positioned fluorine atom and methoxy group that enhance electronic modulation and metabolic stability. This ortho-substituted benzoic acid derivative integrates readily into complex synthetic scaffolds, offering improved solubility and reactivity under standard conditions.
2-Fluoro-3-methoxybenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-fluoro and meta-methoxy substituents provide predictable electronic modulation and enhanced metabolic stability. The carboxylic acid functionality facilitates direct coupling reactions, amide formation, or ester derivatization, offering broad utility in API development workflows. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: