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CS-W001157 4
Total: USD 88.00

(6-(Aminomethyl)pyridin-3-yl)boronic acid

  • CAS No. 1375452-67-7

  • Cat. No. CS-0490446
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(6-(Aminomethyl)pyridin-3-yl)boronic acid|CS-0490446

Structure of 1375452-67-7

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General Information

  • CAS No. 1375452-67-7
  • Cat. No. CS-0490446
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉BN₂O₂
  • Molecular Weight 151.96
  • Synonym(s) None
  • SMILES NCC1N=CC(=CC=1)B(O)O

Description

This boronate moiety integrates a pyridine-based scaffold with an aminomethyl handle, enabling efficient coupling in transition-metal-catalyzed transformations. The pendant amine facilitates purification and functionalization, while the boronic acid group delivers high reactivity under mild conditions. Bench-stable and moisture-tolerant, this reagent streamlines access to bioactive heterocycles in medicinal chemistry workflows.

Application

(6-(Aminomethyl)pyridin-3-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. The pendant amine group provides orthogonal functionality for further derivatization, while the boronic acid moiety offers excellent bench stability and compatibility with diverse reaction partners. Its utility is well-established in constructing bioactive heterocyclic scaffolds and functionalized aryl systems.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   79.37
  • LogP   -1.7799
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   2

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