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CS-W001157 4
Total: USD 88.00

4-Isopropyl-1h-pyrazole

  • CAS No. 13753-53-2

  • Cat. No. CS-0273870
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Isopropyl-1h-pyrazole|CS-0273870

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General Information

  • CAS No. 13753-53-2
  • Cat. No. CS-0273870
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀N₂
  • Molecular Weight 110.16
  • Synonym(s) 4-propan-2-yl-1H-pyrazole
  • SMILES CC(C)C1=CNN=C1

Description

4-Isopropyl-1H-pyrazole features a sterically hindered pyrazole core with enhanced solubility in organic media, enabling efficient integration into catalytic systems and heterocyclic synthesis. This bench-stable scaffold delivers robust performance under standard conditions, facilitating the construction of complex nitrogen-containing architectures.

Application

4-Isopropyl-1H-pyrazole serves as a versatile heterocyclic building block in medicinal chemistry and process development. Its pyrazole core provides robust stability and favorable pharmacokinetic properties, while the isopropyl substituent enhances lipophilicity and steric control. The compound functions effectively in transition-metal-catalyzed couplings and acts as a scaffold for bioactive molecule synthesis, offering predictable reactivity and ease of purification in standard bench-scale operations.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H225-H315-H319
Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P280-P302+P352-P362+P364-P370+P378-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   1.5331
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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