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CS-W001157 4
Total: USD 88.00

2-(1H-Pyrazol-4-yl)propan-2-ol

  • CAS No. 23585-56-0

  • Cat. No. CS-0642007
  • Purity≥98%
  • MDL No.MFCD26679904

*For research and further manufacturing use only, not for direct human use.

2-(1H-Pyrazol-4-yl)propan-2-ol|CS-0642007

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General Information

  • CAS No. 23585-56-0
  • Cat. No. CS-0642007
  • Purity ≥98%
  • MDL No. MFCD26679904
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀N₂O
  • Molecular Weight 126.16
  • Synonym(s) None
  • SMILES OC(C)(C)C1=CNN=C1

Description

This bench-stable pyrazole derivative features a tertiary alcohol moiety flanked by an electron-rich pyrazolyl ring, enabling straightforward incorporation into functionalized scaffolds. The sterically hindered structure enhances stability under standard reaction conditions, facilitating use in synthetic workflows requiring robustness and predictable reactivity.

Application

2-(1H-Pyrazol-4-yl)propan-2-ol serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds. Its tertiary alcohol functionality offers enhanced stability and facilitates downstream functionalization through substitution or oxidation. The pyrazole moiety provides strong hydrogen-bonding capacity and π-stacking potential, contributing to target affinity in kinase inhibitors and other pharmaceutical candidates. This compound exhibits excellent bench stability, simplifies purification, and demonstrates broad compatibility with standard coupling and protection protocols in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   48.91
  • LogP   0.6371
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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