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CS-W001157 4
Total: USD 88.00

7-Bromocinnoline

  • CAS No. 1375108-47-6

  • Cat. No. CS-W007204
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Bromocinnoline|CS-W007204

Structure of 1375108-47-6

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General Information

  • CAS No. 1375108-47-6
  • Cat. No. CS-W007204
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrN₂
  • Molecular Weight 209.04
  • Synonym(s) None
  • SMILES BrC1=CC2=NN=CC=C2C=C1

Description

7-Bromocinnoline features a bromine substituent at the 7-position of the cinnoline core, enabling direct functionalization in cross-coupling reactions. This electron-deficient heteroaromatic scaffold integrates readily into pharmaceutical and agrochemical scaffolds, offering enhanced reactivity under standard conditions.

Application

7-Bromocinnoline serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions to construct biaryl and heteroaryl scaffolds. Its bromine substituent exhibits high reactivity in Suzuki, Stille, and Negishi couplings, while the cinnoline core provides a stable, electron-deficient platform for further functionalization. The compound demonstrates excellent bench stability and compatibility with diverse reaction conditions, facilitating efficient access to complex nitrogen-containing heterocycles relevant to medicinal chemistry and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   2.3923
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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