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CS-W001157 4
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(S)-tert-Butyl 2-methylpyrrolidine-1-carboxylate

  • CAS No. 137496-71-0

  • Cat. No. CS-0042558
  • Molecule weight185.26
  • Purity≥98%
  • MDL No.MFCD06858469

*For research and further manufacturing use only, not for direct human use.

(S)-tert-Butyl 2-methylpyrrolidine-1-carboxylate|CS-0042558

Structure of 137496-71-0

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General Information

  • CAS No. 137496-71-0
  • Cat. No. CS-0042558
  • Purity ≥98%
  • MDL No. MFCD06858469
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉NO₂
  • Molecular Weight 185.26
  • Synonym(s) tert-butyl (2R)-2-methylpyrrolidine-1-carboxylate
  • SMILES O=C(N1[C@@H](C)CCC1)OC(C)(C)C

Synthesis

  • Route1
    • Tert-butyl (R)-2-(((methylsulfonyl)oxy)methyl)pyrrolidine-1-carboxylate|CS-0491322
      132482-10-1
    • ~85%
    • In-stock
      (S)-tert-Butyl 2-methylpyrrolidine-1-carboxylate|CS-0042558
      137496-71-0

    References

    • ELI LILLY AND COMPANY Patent: WO2006/19833 A1, 2006 ; Location in patent: Page/Page column 61 ; WO 2006/019833 A1
  • Route2
    • (R)-tert-Butyl 2-((tosyloxy)methyl)pyrrolidine-1-carboxylate|CS-0541701
      128510-88-3
    • ~80%
    • In-stock
      (S)-tert-Butyl 2-methylpyrrolidine-1-carboxylate|CS-0042558
      137496-71-0

    References

    • Ku, Yi-Yin; Cowart, Marlon D.; Sharma, Padam N. Patent: US2004/260100 A1, 2004 ; Location in patent: Page 8 ; US 20040260100 A1
  • Route3
    • In-stock
      tert-Butyl pyrrolidine-1-carboxylate|CS-W001661
      86953-79-9
    • null|null
      77-78-1
    • ~74%
    • In-stock
      (S)-tert-Butyl 2-methylpyrrolidine-1-carboxylate|CS-0042558
      137496-71-0

    References

    • Bertini Gross; Beak Journal of the American Chemical Society, 2001 , vol. 123, # 2 p. 315 - 321

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06,GHS09
Signal Word : Danger
UN#: 2922
Class : 8 (6.1)
Packing Group : Ⅲ
Hazard Statements : H227-H301-H315-H319-H335-H410
Precautionary Statements : P261-P273-P280

Quality Control

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   2.4058
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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