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CS-W001157 4
Total: USD 88.00

2,4,6-Trimethylbenzenesulfinamide

  • CAS No. 137280-49-0

  • Cat. No. CS-0162506
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,4,6-Trimethylbenzenesulfinamide|CS-0162506

Structure of 137280-49-0

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General Information

  • CAS No. 137280-49-0
  • Cat. No. CS-0162506
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NOS
  • Molecular Weight 183.27
  • Synonym(s) None
  • SMILES O=S(C1=C(C)C=C(C)C=C1C)N

Description

2,4,6-Trimethylbenzenesulfinamide features a sterically shielded sulfinamide group attached to a highly substituted aromatic ring. This configuration imparts exceptional stability and resistance to oxidation, enabling reliable use in asymmetric synthesis. The electron-rich aryl core enhances reactivity in transition-metal-catalyzed transformations. Its bench-stable nature simplifies handling in multi-step sequences.

Application

2,4,6-Trimethylbenzenesulfinamide serves as a stable, bench-ready sulfinamide source for stereoselective synthesis of sulfimines and sulfoxides. Its electron-donating trimethylphenyl group enhances reactivity in asymmetric α-amination and C–H functionalization processes. The compound exhibits excellent functional group tolerance and facilitates straightforward purification, making it a practical choice for complex molecule assembly in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.09
  • LogP   1.59316
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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