(R)-tert-Butyl (2-amino-1-phenylethyl)carbamate

Name: (R)-tert-Butyl (2-amino-1-phenylethyl)carbamate
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CAS No. 137102-65-9
Cat. No. CS-0433178
Purity≥97%
MDL No.MFCD11849114

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(R)-tert-Butyl (2-amino-1-phenylethyl)carbamate|CS-0433178

Structure of 137102-65-9

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Description

(R)-tert-Butyl (2-amino-1-phenylethyl)carbamate is a chiral building block featuring a stereodefined amino alcohol scaffold. This bench-stable, moisture-tolerant reagent integrates readily into asymmetric synthesis workflows. The protected amine and phenyl-substituted carbon center enable direct functionalization in peptide mimicry and catalytic transformations.

Application

(R)-tert-Butyl (2-amino-1-phenylethyl)carbamate serves as a key chiral building block in asymmetric synthesis, enabling the stereoselective construction of phenylethylamine derivatives. Its robust tert-butyl carbamate protecting group offers excellent bench stability and facilitates straightforward deprotection under mild acidic conditions. The molecule functions effectively in peptide coupling, reductive amination, and transition-metal-catalyzed transformations, providing access to biologically relevant scaffolds with high enantiomeric purity.

General Information

CAS No. 137102-65-9
Cat. No. CS-0433178
Purity ≥97%
MDL No. MFCD11849114
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₂₀N₂O₂
Molecular Weight 236.31
Synonym(s) Carbamic acid, (2-amino-1-phenylethyl)-, 1,1-dimethylethyl ester, (R)-
SMILES O=C(OC(C)(C)C)N[C@H](C1=CC=CC=C1)CN

Computational Chemistry Data

TPSA 64.35
LogP 2.2111
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-tert-Butyl (2-amino-1-phenylethyl)carbamate

CAS No. 137102-65-9

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