Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-[(tert-Butyldimethylsilyloxy)methyl]aniline

  • CAS No. 131230-76-7

  • Cat. No. CS-0009163
  • Purity≥95%
  • MDL No.MFCD20483304

*For research and further manufacturing use only, not for direct human use.

4-[(tert-Butyldimethylsilyloxy)methyl]aniline|CS-0009163

Structure of 131230-76-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 131230-76-7
  • Cat. No. CS-0009163
  • Purity ≥95%
  • MDL No. MFCD20483304
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₃NOSi
  • Molecular Weight 237.41
  • Synonym(s) 4-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]benzenamine
  • SMILES NC1=CC=C(C=C1)CO[Si](C)(C)C(C)(C)C

Description

This silyl-protected aniline derivative features a tert-butyldimethylsilyloxy methyl group that confers enhanced stability and solubility in organic media. The protected amine enables selective deprotection under mild conditions, facilitating downstream functionalization in complex synthesis workflows.

Application

4-[(tert-Butyldimethylsilyloxy)methyl]aniline serves as a versatile protected phenolic building block, enabling selective functionalization at the aniline nitrogen while maintaining stability under standard synthetic conditions. The tert-butyldimethylsilyl (TBS) group provides excellent bench stability and facilitates orthogonal deprotection in late-stage synthesis. Its compatibility with common coupling reactions and tolerance to a range of functional groups make it particularly useful in medicinal chemistry workflows requiring controlled derivatization of aromatic amines.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   35.25
  • LogP   3.7906
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 131230-76-7 sigma131230-76-7 manufacturer131230-76-7 price131230-76-7 structure131230-76-7 SDSbuy 131230-76-7131230-76-7 supplier131230-76-7 uses131230-76-7 molecular weightprice of 131230-76-7131230-76-7 chemical name formula of 131230-76-7
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label