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CS-W001157 4
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(R)-tert-Butyl (2-amino-1-phenylethyl)carbamate

  • CAS No. 137102-65-9

  • Cat. No. CS-0433178
  • Molecule weight236.31
  • Purity≥97%
  • MDL No.MFCD11849114

*For research and further manufacturing use only, not for direct human use.

(R)-tert-Butyl (2-amino-1-phenylethyl)carbamate|CS-0433178

Structure of 137102-65-9

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General Information

  • CAS No. 137102-65-9
  • Cat. No. CS-0433178
  • Purity ≥97%
  • MDL No. MFCD11849114
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₀N₂O₂
  • Molecular Weight 236.31
  • Synonym(s) Carbamic acid, (2-amino-1-phenylethyl)-, 1,1-dimethylethyl ester, (R)-
  • SMILES O=C(OC(C)(C)C)N[C@H](C1=CC=CC=C1)CN

Description

(R)-tert-Butyl (2-amino-1-phenylethyl)carbamate is a chiral building block featuring a stereodefined amino alcohol scaffold. This bench-stable, moisture-tolerant reagent integrates readily into asymmetric synthesis workflows. The protected amine and phenyl-substituted carbon center enable direct functionalization in peptide mimicry and catalytic transformations.

Application

(R)-tert-Butyl (2-amino-1-phenylethyl)carbamate serves as a key chiral building block in asymmetric synthesis, enabling the stereoselective construction of phenylethylamine derivatives. Its robust tert-butyl carbamate protecting group offers excellent bench stability and facilitates straightforward deprotection under mild acidic conditions. The molecule functions effectively in peptide coupling, reductive amination, and transition-metal-catalyzed transformations, providing access to biologically relevant scaffolds with high enantiomeric purity.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   2.2111
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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