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Structure of 137049-00-4
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1-Methyl-1H-imidazole-4-sulfonyl chloride is a bench-stable, moisture-tolerant sulfonyl chloride reagent featuring a sterically accessible sulfonamide handle. This electrophilic moiety integrates readily into synthetic scaffolds under mild conditions, enabling efficient derivatization of nucleophiles such as amines and alcohols. The electron-deficient imidazole ring enhances reactivity while maintaining compatibility with diverse functional groups.
1-Methyl-1H-imidazole-4-sulfonyl chloride serves as a versatile sulfonylating agent for the efficient introduction of the 1-methyl-1H-imidazol-4-ylsulfonyl group into diverse substrates. Its reactivity enables selective sulfonation of nucleophiles such as amines and alcohols under mild conditions, offering high functional group tolerance and ease of purification. The imidazole scaffold provides enhanced stability and solubility, making it well-suited for applications in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: