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CS-W001157 4
Total: USD 88.00

2-Bromobenzo[d]thiazol-4-amine

  • CAS No. 1368320-74-4

  • Cat. No. CS-0041866
  • Purity≥98%
  • MDL No.MFCD22031293

*For research and further manufacturing use only, not for direct human use.

2-Bromobenzo[d]thiazol-4-amine|CS-0041866

Structure of 1368320-74-4

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General Information

  • CAS No. 1368320-74-4
  • Cat. No. CS-0041866
  • Purity ≥98%
  • MDL No. MFCD22031293
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrN₂S
  • Molecular Weight 229.10
  • Synonym(s) None
  • SMILES NC1=C2N=C(Br)SC2=CC=C1

Description

2-Bromobenzo[d]thiazol-4-amine features a brominated benzothiazole core with a strategically positioned amine group, enabling direct coupling in cross-coupling reactions. This electron-deficient heterocycle integrates readily into bioactive scaffolds, offering enhanced metabolic stability and improved solubility in polar solvents under standard conditions.

Application

2-Bromobenzo[d]thiazol-4-amine serves as a versatile building block for the synthesis of biologically active heterocycles and pharmaceutical intermediates. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the amino group facilitates further derivatization. The compound exhibits good bench stability and compatibility with standard synthetic protocols, making it well-suited for iterative functionalization in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.641
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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