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(6-Methylpyridin-2-yl)methanamine hydrochloride

  • CAS No. 1365836-53-8

  • Cat. No. CS-0100448
  • Purity≥97%
  • MDL No.MFCD09878926

*For research and further manufacturing use only, not for direct human use.

(6-Methylpyridin-2-yl)methanamine hydrochloride|CS-0100448

Structure of 1365836-53-8

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General Information

  • CAS No. 1365836-53-8
  • Cat. No. CS-0100448
  • Purity ≥97%
  • MDL No. MFCD09878926
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁ClN₂
  • Molecular Weight 158.63
  • Synonym(s) None
  • SMILES NCC1=NC(C)=CC=C1.[H]Cl

Description

This bench-stable amine features a 6-methylpyridin-2-yl scaffold that enhances electron density at the nitrogen center, enabling efficient coupling in transition metal catalysis. The hydrochloride salt improves solubility and handling, facilitating use in synthetic organic chemistry workflows.

Application

(6-Methylpyridin-2-yl)methanamine hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based pharmacophores. Its amine functionality facilitates straightforward derivatization via amidation, alkylation, and reductive amination, while the methyl-substituted pyridine ring enhances metabolic stability and modulates electronic properties. The hydrochloride salt form ensures excellent solubility and bench stability, simplifying handling and purification in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.27052
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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