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CS-W001157 4
Total: USD 88.00

Biotin-PEG2-acid

  • CAS No. 1365655-89-5

  • Cat. No. CS-0108923
  • Purity≥97%
  • MDL No.MFCD22056305

*For research and further manufacturing use only, not for direct human use.

Biotin-PEG2-acid|CS-0108923

Structure of 1365655-89-5

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General Information

  • CAS No. 1365655-89-5
  • Cat. No. CS-0108923
  • Purity ≥97%
  • MDL No. MFCD22056305
  • Storage -20°C, protect from light, stored under argon
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₉N₃O₆S
  • Molecular Weight 403.49
  • Synonym(s) None
  • SMILES O=C(O)CCOCCOCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O

Description

Biotin-PEG2-acid features a short, hydrophilic PEG spacer linking biotin to a terminal carboxylic acid group. This design enables site-specific conjugation via amine coupling while maintaining high affinity for streptavidin. The molecule exhibits excellent solubility in aqueous buffers and stability under standard handling conditions.

Application

Biotin-PEG2-acid serves as a versatile bifunctional linker for bioconjugation, enabling site-specific labeling via its reactive carboxylic acid group and high-affinity biotin binding. The short PEG spacer enhances solubility and reduces steric hindrance, facilitating efficient conjugation to proteins, antibodies, or solid supports while maintaining functional group integrity under standard coupling conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   125.99
  • LogP   0.3363
  • H_Acceptors   6
  • H_Donors   4
  • Rotatable_Bonds   14

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