(R)-2,2'-Bis(di-p-tolylphosphino)-4,4',6,6'-tetramethoxy)-1,1'-biphenyl

Name: (R)-2,2'-Bis(di-p-tolylphosphino)-4,4',6,6'-tetramethoxy)-1,1'-biphenyl
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1365531-81-2
Cat. No. CS-0108700
Purity≥98%
MDL No.MFCD19443623

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(R)-2,2'-Bis(di-p-tolylphosphino)-4,4',6,6'-tetramethoxy)-1,1'-biphenyl|CS-0108700

Structure of 1365531-81-2

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1365531-81-2
Cat. No. CS-0108700
Purity ≥98%
MDL No. MFCD19443623
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄₄H₄₄O₄P₂
Molecular Weight 698.77
Synonym(s) (4,4',6,6'-Tetramethoxy-2,2'-biphenyldiyl)bis[bis(4-methylphenyl)phosphine]
SMILES CC(C=C1)=CC=C1P(C2=CC=C(C)C=C2)C3=C(C4=C(OC)C=C(OC)C=C4P(C5=CC=C(C)C=C5)C6=CC=C(C)C=C6)C(OC)=CC(OC)=C3

Description

(R)-2,2'-Bis(di-p-tolylphosphino)-4,4',6,6'-tetramethoxy-1,1'-biphenyl is a sterically hindered, electron-rich phosphine ligand designed for palladium-catalyzed cross-coupling reactions. The tetramethoxy substitution enhances solubility and stability under reaction conditions, while the chiral biphenyl backbone provides precise control over stereochemistry in asymmetric transformations. This ligand integrates seamlessly into catalytic systems requiring robust performance and high selectivity.

Application

(R)-2,2'-Bis(di-p-tolylphosphino)-4,4',6,6'-tetramethoxy-1,1'-biphenyl serves as a highly functional, bench-stable ligand in palladium-catalyzed cross-coupling reactions. Its electron-rich phosphine centers enable efficient formation of C–C and C–heteroatom bonds under mild conditions. The tetramethoxy substitution enhances solubility and stability, while the steric bulk supports high selectivity in Suzuki-Miyaura and Negishi couplings. Ideal for complex molecule assembly in medicinal chemistry and materials synthesis.

Safety Information

Download SDS

GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 36.92
LogP 8.13808
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 11

Key Words

1365531-81-2 sigma1365531-81-2 manufacturer1365531-81-2 price1365531-81-2 structure1365531-81-2 SDSbuy 1365531-81-21365531-81-2 supplier1365531-81-2 uses1365531-81-2 molecular weightprice of 1365531-81-21365531-81-2 chemical name formula of 1365531-81-2

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(R)-2,2'-Bis(di-p-tolylphosphino)-4,4',6,6'-tetramethoxy)-1,1'-biphenyl

CAS No. 1365531-81-2

Recommended Products