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Structure of 1360950-77-1
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5-Methyl-1H-indole-4-carboxylic acid features a sterically accessible indole core with a carboxylic acid group at the 4-position and a methyl substituent at the 5-position. This configuration imparts enhanced solubility in polar solvents while maintaining stability under standard bench conditions, enabling direct integration into synthetic routes for bioactive molecule development.
5-Methyl-1H-indole-4-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling direct functionalization at the C4 position via standard carboxylic acid transformations. Its stability under ambient conditions and compatibility with amide coupling, esterification, and decarboxylation protocols make it well-suited for medicinal chemistry campaigns and API intermediate development. The methyl group at C5 provides a handle for further substitution or oxidation, enhancing structural diversity in indole-based libraries.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: