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Structure of 1360927-57-6
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5-Methyl-1H-indazole-4-carboxylic acid features a fused bicyclic core with a methyl group at the 5-position and a carboxylic acid at the 4-position, conferring enhanced solubility and metabolic stability. This scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for kinase inhibitors and targeted therapeutics.
5-Methyl-1H-indazole-4-carboxylic acid serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, enabling efficient derivatization via amide coupling, esterification, and Suzuki-type cross-coupling reactions. Its ortho-functionalized indazole scaffold offers enhanced metabolic stability and favorable pharmacophore geometry, making it suitable for constructing bioactive molecules in drug discovery programs. The compound exhibits good bench stability and facilitates straightforward purification by recrystallization or column chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P233-P261-P264-P271-P280-P302+P352-P304+P340-P362-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: