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CS-W001157 4
Total: USD 88.00

2-Bromo-3-methoxyphenol

  • CAS No. 135999-16-5

  • Cat. No. CS-W005377
  • Purity≥95%
  • MDL No.MFCD09056758

*For research and further manufacturing use only, not for direct human use.

2-Bromo-3-methoxyphenol|CS-W005377

Structure of 135999-16-5

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General Information

  • CAS No. 135999-16-5
  • Cat. No. CS-W005377
  • Purity ≥95%
  • MDL No. MFCD09056758
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇BrO₂
  • Molecular Weight 203.03
  • Synonym(s) None
  • SMILES COC1=CC=CC(O)=C1Br

Description

3-Benzoylbenzoic acid has been used in light-induced reactions on benzophenone-terminated boron-doped diamond (BDD) surfaces and preparation of benzophenone flavonol derivative.

Application

2-Bromo-3-methoxyphenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of substituted phenolic scaffolds. Its bromine and methoxy groups offer orthogonal reactivity for palladium-catalyzed cross-coupling and directed functionalization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic sequences and scale-up applications.

Synthesis

  • Route1
    • null|null
      30778-86-0
    • ~30%
    • In-stock
      2-Bromo-3-methoxyphenol|CS-W005377
      135999-16-5

    References

    • Eli Lilly and Company Patent: US7045545 B1, 2006 ; Location in patent: Page/Page column 22 ;
  • Route2
    • null|null
      146746-58-9
    • ~75%
    • In-stock
      2-Bromo-3-methoxyphenol|CS-W005377
      135999-16-5

    References

    • Pave, Gregoire; Leger, Jean-Michel; Jarry, Christian; Viaud-Massuard, Marie-Claude; Guillaumet, Gerald Journal of Organic Chemistry, 2003 , vol. 68, # 4 p. 1401 - 1408
  • Route3
    • In-stock
      2-Bromobenzene-1,3-diol|CS-W015980
      6751-75-3
    • null|null
      77-78-1
    • ~49%
    • In-stock
      2-Bromo-3-methoxyphenol|CS-W005377
      135999-16-5

    References

    • Luening, Ulrich; Fahrenkrug, Frank European Journal of Organic Chemistry, 2004 , # 14 p. 3119 - 3127

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   2.1633
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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