Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Chloro-2-hydroxybenzonitrile

  • CAS No. 13589-72-5

  • Cat. No. CS-0043964
  • Purity≥97%
  • MDL No.MFCD00219003

*For research and further manufacturing use only, not for direct human use.

5-Chloro-2-hydroxybenzonitrile|CS-0043964

Structure of 13589-72-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 13589-72-5
  • Cat. No. CS-0043964
  • Purity ≥97%
  • MDL No. MFCD00219003
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄ClNO
  • Molecular Weight 153.57
  • Synonym(s) 5-Chlorosalicylonitrile
  • SMILES OC1=C(C=C(Cl)C=C1)C#N

Description

5-Chloro-2-hydroxybenzonitrile features a hydroxyl group ortho to a nitrile moiety on a chlorinated benzene ring, enabling direct participation in coupling reactions and metal coordination. This arrangement imparts enhanced solubility in polar solvents and stability under standard bench conditions, facilitating its use in synthetic intermediates for pharmaceuticals and agrochemicals.

Application

5-Chloro-2-hydroxybenzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzimidazoles, quinoline derivatives, and other heterocyclic scaffolds. The ortho-hydroxynitrile motif facilitates direct cyclization or transition-metal-catalyzed coupling reactions. Its bench-stable nature and tolerance to common functional groups support straightforward purification and scalability in multi-step syntheses.

Synthesis

  • Route1

    References

    • WO2006/115130 A1, ; Page/Page column 53-54 ;
  • Route2

    References

    • US6046212 A1, ;
  • Route3

    References

    • EP1323713 A1, ; EP 1323713 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   44.02
  • LogP   1.91728
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Chloro-2-hydroxybenzonitrile sigma5-Chloro-2-hydroxybenzonitrile manufacturer5-Chloro-2-hydroxybenzonitrile price5-Chloro-2-hydroxybenzonitrile structure5-Chloro-2-hydroxybenzonitrile SDSbuy 5-Chloro-2-hydroxybenzonitrile5-Chloro-2-hydroxybenzonitrile supplier5-Chloro-2-hydroxybenzonitrile uses5-Chloro-2-hydroxybenzonitrile molecular weightprice of 5-Chloro-2-hydroxybenzonitrile5-Chloro-2-hydroxybenzonitrile chemical name formula of 5-Chloro-2-hydroxybenzonitrile
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label