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Structure of 1357946-55-4
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6-Bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine features a dual halogenated pyrazolopyridine core, enabling direct functionalization in cross-coupling reactions. The bromo and iodo substituents occupy electronically distinct positions, offering orthogonal reactivity for sequential derivatization. This scaffold integrates readily into complex heterocyclic systems, particularly in medicinal chemistry applications requiring precise substitution patterns.
6-Bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine serves as a versatile bifunctional building block for the synthesis of complex heterocyclic scaffolds. Its complementary halogenation pattern enables sequential cross-coupling reactions via palladium-catalyzed processes, facilitating efficient construction of biaryl and fused polycyclic systems. The molecule exhibits excellent bench stability and is readily purified by standard chromatographic methods, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: