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CS-W001157 4
Total: USD 88.00

Methyl 2-amino-6-bromobenzoate

  • CAS No. 135484-78-5

  • Cat. No. CS-W006104
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 2-amino-6-bromobenzoate|CS-W006104

Structure of 135484-78-5

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General Information

  • CAS No. 135484-78-5
  • Cat. No. CS-W006104
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈BrNO₂
  • Molecular Weight 230.06
  • Synonym(s) BENZOIC ACID, 2-AMINO-6-BROMO-, METHYL ESTER
  • SMILES O=C(OC)C1=C(Br)C=CC=C1N

Description

Methyl 2-amino-6-bromobenzoate features a brominated aromatic ring paired with complementary amino and ester functionalities, enabling direct incorporation into diverse synthetic scaffolds. This bench-stable compound serves as a key intermediate for pharmaceutical and agrochemical derivatization, offering predictable reactivity under standard coupling conditions.

Application

Methyl 2-amino-6-bromobenzoate serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the amino and bromo positions. Its bench-stable nature and compatibility with Pd-catalyzed cross-coupling reactions facilitate efficient construction of biaryl and heterocyclic scaffolds. The methyl ester group provides orthogonal reactivity for downstream derivatization, while the ortho-amino substituent supports facile cyclization or metal coordination in complex molecule assembly.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.8179
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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