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CS-W001157 4
Total: USD 88.00

4-(Cyclopropylsulfonyl)benzaldehyde

  • CAS No. 1354558-30-7

  • Cat. No. CS-0834796
  • Molecule weight210.25
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(Cyclopropylsulfonyl)benzaldehyde|CS-0834796

Structure of 1354558-30-7

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General Information

  • CAS No. 1354558-30-7
  • Cat. No. CS-0834796
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀O₃S
  • Molecular Weight 210.25
  • Synonym(s) None
  • SMILES O=CC1=CC=C(S(=O)(C2CC2)=O)C=C1

Description

4-(Cyclopropylsulfonyl)benzaldehyde features a cyclopropylsulfonyl group attached to a benzaldehyde scaffold, delivering enhanced solubility and metabolic stability. This electron-withdrawing substituent modulates reactivity while maintaining compatibility with standard synthetic transformations. The molecule integrates readily into pharmaceutical intermediates and functional materials, offering precise control over electronic and steric properties in complex architectures.

Application

4-(Cyclopropylsulfonyl)benzaldehyde serves as a versatile building block in medicinal chemistry, enabling the synthesis of sulfonamide-containing aromatic scaffolds. Its aldehyde functionality facilitates efficient reductive amination, Wittig reactions, and coupling processes, while the cyclopropylsulfonyl group offers enhanced metabolic stability and favorable lipophilicity. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative synthesis campaigns in API development.

Safety Information

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Computational Chemistry Data

  • TPSA   51.21
  • LogP   1.4352
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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