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CS-W001157 4
Total: USD 88.00

4,6-Dichloro-3-methylpyridazine

  • CAS No. 68240-43-7

  • Cat. No. CS-W019067
  • Purity≥96%
  • MDL No.MFCD21604745

*For research and further manufacturing use only, not for direct human use.

4,6-Dichloro-3-methylpyridazine|CS-W019067

Structure of 68240-43-7

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General Information

  • CAS No. 68240-43-7
  • Cat. No. CS-W019067
  • Purity ≥96%
  • MDL No. MFCD21604745
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄Cl₂N₂
  • Molecular Weight 163.01
  • Synonym(s) 3,5-Dichlor-6-methylpyridazin
  • SMILES CC1=NN=C(Cl)C=C1Cl

Description

4,6-Dichloro-3-methylpyridazine is a chlorinated pyridazine derivative featuring two chlorine substituents at the 4- and 6-positions and a methyl group at the 3-position. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds, offering high reactivity in cross-coupling and nucleophilic substitution processes under mild conditions.

Application

4,6-Dichloro-3-methylpyridazine serves as a versatile building block in medicinal chemistry, enabling regioselective functionalization via cross-coupling and nucleophilic substitution reactions. The dichloro pattern facilitates sequential derivatization at C4 and C6 positions, while the methyl group enhances solubility and modulates electronic properties. Its bench-stable nature and compatibility with palladium-catalyzed transformations make it ideal for constructing complex heterocyclic scaffolds in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   2.09182
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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