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CS-W001157 4
Total: USD 88.00

(1-Methyl-1H-[1,2,4]triazol-3-yl)methanol

  • CAS No. 135242-93-2

  • Cat. No. CS-W018912
  • Purity≥95%
  • MDL No.MFCD16710296

*For research and further manufacturing use only, not for direct human use.

(1-Methyl-1H-[1,2,4]triazol-3-yl)methanol|CS-W018912

Structure of 135242-93-2

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General Information

  • CAS No. 135242-93-2
  • Cat. No. CS-W018912
  • Purity ≥95%
  • MDL No. MFCD16710296
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇N₃O
  • Molecular Weight 113.12
  • Synonym(s) None
  • SMILES C[N]1C=NC(=N1)CO

Description

This triazolylmethanol delivers a versatile functional handle for conjugation and derivatization. The methyl-substituted triazole ring enhances stability and solubility, while the primary alcohol enables straightforward coupling reactions under standard conditions. Ideal for building bioconjugates and functionalized scaffolds in medicinal chemistry.

Application

(1-Methyl-1H-[1,2,4]triazol-3-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient access to triazolyl-containing scaffolds via standard functional group transformations. Its bench-stable nature and compatibility with diverse reaction conditions facilitate straightforward incorporation into complex molecules. The molecule functions effectively as a linker or bioisostere in the synthesis of heterocyclic APIs and drug candidates.

Synthesis

  • Route1
    • null|null
      135206-74-5
    • ~99%
    • In-stock
      (1-Methyl-1H-[1,2,4]triazol-3-yl)methanol|CS-W018912
      135242-93-2

    References

    • Tasaka; Teranishi; Matsushita; Tamura; Hayashi; Okonogi; Itoh Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 1 p. 85 - 94

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.94
  • LogP   -0.6926
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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