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Structure of 135124-70-8
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(5-Bromopyridin-3-yl)methanamine features a brominated pyridine core with a primary amine handle, enabling direct coupling in C–N cross-coupling reactions. The electron-deficient ring facilitates nucleophilic substitution, while the pendant amine offers ready derivatization. This bench-stable reagent integrates seamlessly into synthetic routes for bioactive heterocycles and functional materials.
(5-Bromopyridin-3-yl)methanamine serves as a versatile building block for the synthesis of functionalized pyridine derivatives. Its bromo group enables palladium-catalyzed cross-coupling reactions, while the primary amine facilitates conjugation via amidation or reductive amination. The compound exhibits good bench stability and compatibility with standard protecting group strategies, making it well-suited for medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: