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CS-W001157 4
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3-Bromo-5H-pyrrolo[3,4-b]pyridin-7(6H)-one

  • CAS No. 1346809-61-7

  • Cat. No. CS-W000482
  • Purity≥97%
  • MDL No.MFCD20257894
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Bromo-5H-pyrrolo[3,4-b]pyridin-7(6H)-one|CS-W000482

Structure of 1346809-61-7

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Description

3-Bromo-5H-pyrrolo[3,4-b]pyridin-7(6H)-one is a heterocyclic building block featuring a brominated pyrrolopyridinone core. This scaffold delivers a reactive handle for cross-coupling reactions while maintaining stability under standard bench conditions. The molecule integrates readily into complex architectures due to its planar, electron-deficient framework and compatibility with palladium-mediated transformations.

Application

3-Bromo-5H-pyrrolo[3,4-b]pyridin-7(6H)-one serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. The bromine substituent enables efficient Pd-catalyzed cross-coupling reactions, while the lactam functionality offers hydrogen bonding capacity and structural rigidity. Its bench-stable nature and compatibility with diverse reaction conditions facilitate straightforward functionalization in multistep syntheses.

General Information

  • CAS No. 1346809-61-7
  • Cat. No. CS-W000482
  • Purity ≥97%
  • MDL No. MFCD20257894
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrN₂O
  • Molecular Weight 213.03
  • Synonym(s) 3-bromo-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one
  • SMILES BrC1=CN=C2C(CNC2=O)=C1

Computational Chemistry Data

  • TPSA   41.99
  • LogP   1.0875
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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