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tert-Butyl N-[(3R)-5-oxopyrrolidin-3-yl]carbamate

  • CAS No. 1346773-63-4

  • Cat. No. CS-0048007
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl N-[(3R)-5-oxopyrrolidin-3-yl]carbamate|CS-0048007

Structure of 1346773-63-4

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General Information

  • CAS No. 1346773-63-4
  • Cat. No. CS-0048007
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₆N₂O₃
  • Molecular Weight 200.23
  • Synonym(s) (R)-tert-butyl 5-oxopyrrolidin-3-ylcarbaMate
  • SMILES CC(C)(C)OC(=O)N[C@H]1CNC(=O)C1

Description

tert-Butyl N-[(3R)-5-oxopyrrolidin-3-yl]carbamate features a chiral pyrrolidinone core with a bench-stable tert-butyl carbamate protecting group, enabling selective functionalization in asymmetric synthesis. This configuration supports efficient incorporation into complex nitrogen-containing scaffolds under mild deprotection conditions.

Application

tert-Butyl N-[(3R)-5-oxopyrrolidin-3-yl]carbamate serves as a versatile chiral building block for the synthesis of pyrrolidine-containing scaffolds. The protected amine and ketone functionalities enable selective transformations in medicinal chemistry workflows. Its bench-stable nature and compatibility with standard coupling and reduction conditions facilitate efficient access to bioactive heterocycles and peptide analogs.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   67.43
  • LogP   0.3996
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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